Methocarbamol blocks muscular Na v 1.4 channels and decreases isometric force of mouse muscles
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چکیده
منابع مشابه
Isometric and eccentric force generation assessment of skeletal muscles isolated from murine models of muscular dystrophies.
Critical to the evaluation of potential therapeutics for muscular disease are sensitive and reproducible physiological assessments of muscle function. Because many pre-clinical trials rely on mouse models for these diseases, isolated muscle function has become one of the standards for Go/NoGo decisions in moving drug candidates forward into patients. We will demonstrate the preparation of the e...
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ژورنال
عنوان ژورنال: Muscle & Nerve
سال: 2020
ISSN: 0148-639X,1097-4598
DOI: 10.1002/mus.27087